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The Effects of Early Enteral Feeding in Extremely Low Birth-Weight Infants

Korean Journal of Pediatrics 2005;48(7):711-715.
Published online July 15, 2005.
The Effects of Early Enteral Feeding in Extremely Low Birth-Weight Infants
Ga Won Jeon, Sung Eun Park, Chang Won Choi, Jong Hee Hwang, Yun Sil Chang, Won Soon Park
Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
출생체중 1,000 g 미만의 초극소저출생체중아에서 조기장관영양의 효과
전가원, 박성은, 최창원, 황종희, 장윤실, 박원순
성균관대학교 의과대학 삼성서울병원 소아과
Correspondence: 
Won Soon Park, Email: wspark@smc.samsung.co.kr
Abstract
Purpose
: With the recent improved survival of extremely low birth weight infants(ELBWI), enteral feeding has become a major issue. This study investigates the effects of early enteral feeding in ELBWI on their morbidity, duration of hospitalization, and mortality.
Methods
: ELBWI admitted to the neonatal intensive care unit at Samsung Medical Center from November 1994 to April 2004 who survived more than 14 days were enrolled. ELBWI were divided into two groups : an early feeding group(EF), in which enteral feeding was started within 3 days after birth; and a late feeding group(LF), in which enteral feeding was started beyond 3 days after birth. 80 ELBWI came under EF, and 131 ELBWI under LF.
Results
: Birth weight and gestational age did not differ between the two groups. In EF, the time to achieve full enteral feeding and the duration of parenteral nutrition were significantly shorter than in LF. The incidence of bronchopulmonary dysplasia was significantly lower in EF, but the incidences of sepsis, necrotizing enterocolitis, and cholestasis were not different between the two groups. There was no difference in the survival rate between the two groups, but the duration of hospitalization was significantly shorter in EF.
Conclusion
: Early enteral feeding in ELBWI did not increase the incidence of necrotizing enterocolitis and sepsis, but rather decreased the incidence of bronchopulmonary dysplasia and shortened the duration of hospitalization.
Key Words: Early enteral feeding , Extremely low birth weight infant , Trophic feeding


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