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Lower respiratory tract infection of positive antigen test for respiratory syncytial virus on children under 2 years of age

Korean Journal of Pediatrics 2006;49(4):394-400.
Published online April 15, 2006.
Lower respiratory tract infection of positive antigen test for respiratory syncytial virus on children under 2 years of age
Jea Heon Jeong1, Kyoung Hee Moon1, Chang Woo Lee1, Du Young Choi1, Yeun Geun Oh1, Hyang Suk Yoon1, Ji Hyun Cho2, Jong Duck Kim1
1Departments of Pediatrics, College of Medicine, Wonkwang University, Iksan, Korea
2Departments of Laboratory Medicine, College of Medicine, Wonkwang University, Iksan, Korea
2세 이하의 소아에서 respiratory syncytial virus의 항원검사에 양성인 하기도 감염
정재헌1, 문경희1, 이창우1, 최두영1, 오연균1, 윤향석1, 조지현2, 김종덕1
1원광대학교 의과대학 소아과학교실
2원광대학교 의과대학 임상진단의학교실
Jong Duck Kim, Email: kjd20104@wonkwang.ac.kr
: This study was design and performed for evaluations of resent clinical pattern of bronchiolitis caused by RSV infection with children under 2 year of age for 5 years, who were admitted to pediatric ward.
: The inclusion criteria of the patients were children under 24 month-of-age, clinical manifestations of lower respiratory tract infection, and RSV antigen that was detected by a direct immunofluorescence test from the nasal secretions. The additional laboratory and simple chest X-ray findings were reviewed from the medical records of children who were admitted Wonkwang university hospital from Jan. 1999 to Dec. 2003.
: In the 5 year study duration, 127 patients were enrolled and outbreak of RSV bronchiolitis took place in 2001. The 80 cases(63 percent) of RSV infection were concentrated in later autumn and winter. Number of the cases show coughing were 120(94.5 percent), but rale was audible in 78 cases(61.4 percent). Dyspnea, wheezing, and intercostal retraction were noticed in 27(21.3 percent), 21(16.5 percent), and 4(3 percent) cases respectively. The most common chest X-ray finding was hyperinflation of the lung that was noticed in 110 cases(86.6 percent). Care with mechanical ventilator for more than 2 days required in 5 cases.
: Lower respiratory tract infection by RSV was common in late autumn and winter season but year-round infection was noticed. The severity of RSV respiratory tract infectiontakes in some degree a grave course. So we suggest that population-based surveillance of acute respiratory infection due to RSV is necessary for assessment of prevalence and epidemiology of this disease.
Key Words: Bronchiolitis , Respiratory syncytial virus

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