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Auditory brainstem response (ABR) results in NICU graduates

Korean Journal of Pediatrics 2006;49(12):1301-1307.
Published online December 15, 2006.
Auditory brainstem response (ABR) results in NICU graduates
Hee-Joung Choi, Tae-ho Lee, Ki-Won Oh, Heng-Mi Kim
Department of Pediatrics, College of Medicine, Kyungpook National University, Daegu, Korea
신생아 집중치료실 퇴원아의 청성뇌간반응(ABR) 결과에 미치는 위험인자 및 경과
최희정, 이태호, 오기원, 김행미
경북대학교 의과대학 소아과학교실
Heng-Mi Kim, Email: hmkim@knu.ac.kr
: Hearing loss is one of the most common birth defects, and early detection and intervention positively impact language/speech and cognitive development. It has been reported that NICU graduates have a high incidence of hearing loss. So we investigated the incidence, risk factors and clinical outcome of hearing loss in NICU graduates.
: This study involved neonatal auditory brainstem response (ABR) testing of newborn infants who graduated from the NICU of Kyungpook National University Hospital during a 3-year period (between July 2002 and June 2005) and subsequent follow-up of these infants.
: ABR evaluations were performed on 474 infants. Of these infants, 64 showed abnormal ABR (13.5 percent). Of 128 ears from these 64 infants, two ears (1.6 percent) and 10 ears (7.8 percent) were classified as severe and profound hearing loss, respectively. The infants with abnormal ABR had higher incidence of prematurity, low birth weight, very low birth weight, neonatal asphyxia, cranio-facial malformation and amikacin treatment over 15 days (P<0.05). In infants with hyperbilirubinemia, the peak level of serum bilirubin, duration of phototherapy and exchange transfusion were not associated with the higher incidence of hearing loss. Follow-up ABR evaluation was performed on 15 infants with abnormal ABR at 8.8 ¡¾ 4.4 months. In follow-up ABR, 80.0% showed improvement or normalization of threshold sensitivity.
: NICU graduates exhibit high risk for hearing loss. Systemic and effective hearing assessment program is needed for these high risk infants.
Key Words: Intensive care , Newborn , Hearing loss , Auditory brainstem response

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