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Prenatal diagnosis and clinical course of restrictive foramen ovale in otherwise normal heart

Korean Journal of Pediatrics 2007;50(3):268-271.
Published online March 15, 2007.
Prenatal diagnosis and clinical course of restrictive foramen ovale in otherwise normal heart
Ji Joung Lee1, Min A Lee2, Yun ee Rhee2, Mea Young Chang1, Hong Ryang Kil1
1Departments of Pediatrics, College of Medicine, Chungnam National University, Daejon, Korea
2Departments of Gynecology, College of Medicine, Chungnam National University, Daejon, Korea
단순 조기 난원공 협착의 산전 진단과 임상경과
이지정1, 이민아2, 이윤아2, 장미영1, 길홍량1
1충남대학교 의과대학 소아과학교실
2충남대학교 의과대학 산부인과학교실
Correspondence: 
Hong Ryang Kil, Email: gilhong@cnu.ac.kr
Abstract
Purpose
: Premature narrowing of the foramen ovale is rare but serious clinical entity. Prenatal narrowing or obstruction of the foramen ovale shows symptoms such as right heart failure, fetal hydrops, triscupid regurgitation, left heart obstructive disease, and supraventricular tachycardia. This study aimed to assess the prenatal diagnosis and postnatal clinical course of restrictive foramen ovale in utero in otherwise normal heart.
Methods
: The subjects were five patients diagnosed with restrictive foramen ovale in utero from January 2001 to June 2005 at Chungnam National University Hospital. The diagnostic criteria was defined when the maximum diameter in a 4-chamber view is less than 2.5 mm and there is a continuous doppler velocity at the foramen ovale of more than 0.6m/s.
Results
: At the time of diagnosis of restrictive foramen ovale, gestation age was 34∼37 wks, and chief complaints were fetal arrhythmia(2 cases), pericardial effusion, Ebstein anomaly and subaortic stenosis. Two cases which were diagnosed fetal hydrops and supraventricular tachycardia delivered by emergent cesarian section. Five cases were found to have right heart dilatation on echocardiogram after birth, but right heart dilatation became normalized at day 7 after birth and the clinical courses were not eventful.
Conclusion
: Identifying an obstructed foramen ovale in the fetus warrants the further search for additional cardiac and extracardiac anomalies, which may alter the prognosis. Delivery should be induced if possible in cases of foramen ovale obstruction with signs of cardiac decompensation.
Key Words: Fetal heart , Foramen ovale , Fetal ultrasonography


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