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Complications of transcatheter closure of atrial septal defects using the amplatzer septal occluder

Korean Journal of Pediatrics 2008;51(4):401-408.
Published online April 15, 2008.
Complications of transcatheter closure of atrial septal defects using the amplatzer septal occluder
Seo Jin Jea1, Hyo Jin Kwon1, Gi Young Jang1, Jae Young Lee2, Soo Jin Kim2, Chang Sung Son1, Joo Won Lee1
1Departments of Pediatrics, College of Medicine, Korea University, Ansan, Korea
2Departments of Pediatric Cardiology, Sejong Heart Institute, Sejong General Hospital, Bucheon, Korea
심방 중격 결손의 경피적 폐쇄술 후 발생한 합병증에 관한 연구
제서진1, 권효진1, 장기영1, 이재영2, 김수진2, 손창성1, 이주원1
1고려대학교 의과대학 소아과학교실
2부천세종병원 소아과
Correspondence: 
Gi Young Jang, Email: jgynhg@dreamwiz.com
Abstract
Purpose
: Transcatheter closure of atrial septal defects (ASD) is currently established therapy as an alternative to surgery. But rarely, complications are reported in some studies. We report early and intermediate term complications associated with transcatheter closure of atrial septal defects using the Amplatzer septal occluder (ASO).
Methods
: From June 2003 to May 2006, 64 patients underwent transcatheter closure of secundum ASD or patent foramen ovale using the ASO. The ratio of male to female was 1:2.4, the median age was 17 years (range: 2.6-64 years) and their median weight was 47.5 kg (range: 2.6-64 kg).
Results
: The median diameter of ASD measured with transthoracic or transesophageal echocardiography was 15 mm (range: 6-28 mm), the median balloon stretched diameter was 18 mm (range: 6.5-34 mm), and the median size of device was 19.5 mm (range: 6-36 mm), was little difference with balloon stretched diameter. There were 10 cases of complications: arrhythmia (2), device malformation (2), aorta to right atrial fistula (1), hemolytic anemia (1), mitral valve encroachment (1), malposition (1), residual shunt (1), and inferior vena cava perforation (1).
Conclusion
: Transcatheter closure of ASD using ASO is effective and safe therapy. However, significant complications such as aorta to atrial fistula, atrial erosion, or device embolization can happen, so an appropriate selection of patient and device in relevance to size and anatomy of ASD is important for successful closure.
Key Words: Atrial septal defect, Transcatheter closure, Complications


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