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Epidemiologic study of Kawasaki disease in 6 months old and younger infants

Korean Journal of Pediatrics 2008;51(12):1320-1323.
Published online December 15, 2008.
Epidemiologic study of Kawasaki disease in 6 months old and younger infants
Yong Won Park1, Ji Whan Han2, In Sook Park3, Chang Hwi Kim4, Sung Ho Cha5, Jae Sook Ma6, Joon Sung Lee2, Tae Chan Kwon7, Sang Bum Lee8, Chul Ho Kim1, Heung Jae Lee9, Yong Soo Yun10
1Department of Pediatrics, College of Medicine, Inje University, Seoul, Korea
2Department of Pediatrics, College of Medicine, Catholic University, Seoul, Korea
3Department of Pediatrics, College of Medicine, University of Ulsan, Seoul, Korea
4Department of Pediatrics, College of Medicine, Soonchunhyang University, Korea
5Department of Pediatrics, College of Medicine, Kyunghee University, Seoul, Korea
6Department of Pediatrics, College of Medicin, Chonnam National University, Kwangju, Korea
7Department of Pediatrics, College of Medicine, Keimyung University, Taegu, Korea
8Department of Pediatrics, College of Medicine, Kyungpook National University, Taegu, Korea
9Department of Pediatrics, College of Medicine, Sungkyunkwan University, Seoul, Korea
10Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea
6개월 이하 영아에서의 가와사끼병의 역학적 연구
박용원1, 한지환2, 박인숙3, 김창휘4, 차성호5, 마재숙6, 이준성2, 권태찬7, 이상범8, 김철호1, 이흥재9, 윤용수10
1인제대학교 의과대학 소아과학교실
2가톨릭대학교 의과대학 소아과학교실
3울산대학교 의과대학 소아과학교실
4순천향대학교 의과대학 소아과학교실
5경희대학교 의과대학 소아과학교실
6전남대학교 의과대학 소아과학교실
7계명대학교 의과대학 소아과학교실
8경북대학교 의과대학 소아과학교실
9성균관대학교 의과대학 소아과학교실
10서울대학교 의과대학 소아과학교실
Yong Won Park, Email: yongpw@hanmail.net
: The aim of this study was to investigate the epidemiologic status of Kawasaki disease (KD) in infants ≤6 months of age.
: For the epidemiologic study of KD in Korea, data from 22,674 KD patients were collected from 1997 to 2005 on a 3-year basis by a retrospective survey. From this survey, data of 1,739 KD patients ≤6 months of age were analyzed and compared with those of KD patients >6 months of age.
: A total of 1,739 patients ≤6 months of age, including 1,088 males and 651 females, represented 7.7% of total KD patients. These subjects included 22 patients aged <1 month, 171 patients aged 1-2 months, 304 patients aged 2-3 months, 407 patients aged 3-4 months, 372 patients aged 4-5 months, and 463 patients aged 5-6 months. Their mean age of onset was 4.3 months, and the male-to-female ratio was 1.67:1. Incidences of coronary arterial (CA) abnormalities (21.0% versus 18.7%) and CA aneurysms (4.7% versus 3.1%) detected by echocardiography showed differences between patients with KD younger and older than 6 months, respectively.
: Comparison of data from KD patients >6 months old with data from 1,739 KD patients ≤6 months old showed significantly higher incidences of CA abnormalities and CA aneurysms in the younger patients.
Key Words: Mucocutaneous lymph node syndrome, Coronary aneurysm, Epidemiology, Infant

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