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Methemoglobinemia development after ingestion of a chinese herbal medicine: A case report

Korean Journal of Pediatrics 2008;52(3):385-388.
Published online March 15, 2009.
Methemoglobinemia development after ingestion of a chinese herbal medicine: A case report
Se Eun Hyun1, Pil Joo Hwang1, Kyung Pil Nam2, Eun Gyong Yoo1, Man Yong Han1
1Department of Pediatrics, Pochon Medical College, Bundang CHA Hopital
2Department of Civil and Environment Engineering, Seoul National University
한약 복용 후 발생한 메트헤모글로빈혈증 1예
현세은1, 황필주1, 남경필2, 유은경1, 한만용1
1포천중문의과대학교 소아과학교실
2서울대학교 건설환경공학부
Correspondence: 
Man Yong Han, Email: drmesh@gmail.com
Received: 18 August 2008   • Revised: 25 September 2008   • Accepted: 26 October 2008
Abstract
An 8-year-old girl visited the emergency room with perioral cyanosis and dyspnea, which had developed 20 hrs prior to the hospital visit. She had taken a Chinese herbal medication for 3 days prior to the onset of the symptoms. A co-oximeter examination revealed a methemoglobin level of 23.7%. An intravenous infusion of methylene blue was administered. Chemical analysis of the herbal medication revealed an ammonia (NH3) level of 239.41 mg/L. More studies are needed on the correlation between methemoglobinemia and the components of Chinese herbal medicines.
Key Words: Methemoglobinemia, Nitrate, Ammonia, Chinese herbal medicines, Children


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