| Facial palsy as the presenting symptom of acute myeloid leukemia
in children: Three cases with stem cell transplantatio |
|
Hee Jo Baek, Dong Kyun Han, Young Ok Kim, Ic Sun Choi, Tai Ju Hwang, Hoon Kook |
|
Department of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Gwangju, Korea |
| 안면마비로 초기 발현된 소아 급성골수성백혈병: 조혈모세포이식으로 성공적으로 치료한 3예 |
|
백희조, 한동균, 김영옥, 최익선, 황태주, 국훈 |
|
전남대학교 의과대학 화순전남대학교병원 소아과학교실 |
Correspondence:
Hoon Kook, Email: hoonkook@chonnam.ac.kr
|
|
|
|
|
| Abstract |
|
Facial palsy as the presenting symptom of leukemia is very rare, especially in acute myeloid leukemia. A review of the medical literature identified reports on 8 children with AML who had facial paralysis as the presenting sign. Whole brain irradiation (WBI) has been applied in most cases. We present the cases of 3 such children. Achieving a remission without WBI, the patients underwent stem cell transplantations (SCTs). Two patients remain event-free 52 months and 62 months after allotransplants. Facial palsy was the harbinger of leukemic relapse in one case after autotransplant. This patient is disease-free 59 months after unrelated SCT rescue. Facial palsy persisted in 2 cases. Allogeneic SCT without WBI may be an effective therapy in patients presenting with facial palsy. A brief review of the literature is presented here. |
| Key Words:
Facial palsy, Acute myeloid leukemia, Whole brain irradiation, Stem cell transplantation, Children |
|
PDF Links
Download Citation
