| High-dose caspofungin salvage in a very-low-birth-weight
infant with refractory candidemia |
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Eun Sun Seo1, Geun Hwa Park1, Sung Mi Kim1, Hye An Jung2, Byoung Kuk Kim3 |
1Department of Pediatics, Busan St. Mary`s Medical Center, Korea
2Department of Radiology, Busan St. Mary`s Medical Center, Korea
3Department of clinical pathology, Busan St. Mary`s Medical Center, Korea |
| 극소 저체중 출생아의 난치성 칸디다혈증에서 고용량 Caspofungin 구제요법 |
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서은선1, 박근화1, 김성미1, 정혜안2, 김병국3 |
1부산성모병원 소아청소년과
2부산성모병원 영상의학과
3부산성모병원 진단검사의학과 |
Correspondence:
Sung Mi Kim, Tel: +82.51-933-7984, Fax: +82.51-936-7531, Email: ksm7090@hanmail.net
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| Abstract |
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Candidiasis is one of the most common causes of late-onset infection among very-low-birth-weight infants (VLBW) in most neonatal intensive care units and is associated with significant morbidity and mortality. Standard therapy consists of the administration of amphotericin B, amphotericin B complex, and fluconazole. In many cases, candidiasis is not easily eradicated, despite the administration of these drugs. We report our experience of the addition of high-dose caspofungin to the conventional antifungal drugs in a VLBW infant with refractory candidemia. |
| Key Words:
Candidiasis, Caspofungin, Infant, Very low birth weight |
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