Clinical observation on juvenile theumatoid arthritis. |
Sung Sub Shim, Chan Yung Kim |
Department of Pediatrics, Pusan National University, College of Medicine, Pusan, Korea |
소아기 류마티양 관절염에 대한 임상적 고찰 |
심성섭, 김찬영 |
부산대학교 의과대학 소아과학교실 |
Received: 12 February 1991 • Accepted: 15 April 1991 |
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Abstract |
The authors analyzed the clinical features, and the therapeutic responses in 29 patients with
juvenile rheumatoid arthritis who were diagnosed and followed at Department of Pediatrics, Pusan
National University Hospital from 1980. 1 to 1990. 6.
The following results were obtained
1) Of the total 29 patients, 12cases (41.4%) were pauciarticular type II and 7cases (24.2%) were
polyarticular RF(—) type. Seventeen cases (58.7%) were 8-11 yrs and male to female ratio was 1.2:
1. It was prevalent in summer (34.5%).
2) The symptoms and signs on admission were arthralgia (93.1%), fever (62.0%), and joint swelling
(41.4%) and the following extraarticular manifestation; GI symptom (34.5%), hepatosplenomegaly
(10.3%), rash (10.3%), lymphadenopathy (6.9%). The most frequently involved joints were the knees
(79.3%), followed by ankles (65.5%).
3) Laboratory examination showed anemia (24.1%), leukocytosis (62.1%), increased ESR (55.2%),
and ANA(+) (7.0%), RF(+) (13.8%). HLA B27 was examined in 5 cases of pauciarticular type II and
positive in 2 cases (40.0%).
4) In radiologic finidngs, early changes were found in 10 cases (34.7%) and late changes in 4 cases
(13.8%).
5) Patients were treated with salicylate and steroid (48.3%), and salicylate only (41.4%). According
to ARA functional class, 7cases (24.1%) were included in Class I, and 2cases in Class IV before
treatment and then 20 cases (69.0%) achieved complete functional capacity (Class 1) at follow up. |
Key Words:
Juvenile rheumatoid arthritis |
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