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Observation on neurocysticercosis in childhood.

Journal of the Korean Pediatric Society 1991;34(6):877-889.
Published online June 30, 1991.
Observation on neurocysticercosis in childhood.
Hae Jung Park1, Seong Hee Jang1, Se Hee Hwang1, Jae Il Sohn1, Yong Seung Hwang1, Kyu Chang Wang2, Byug Kyu Cho2, In One Kim3, Kyung Mo Yeun3, Je Geun Chi4, Seung Yull Cho5
1Department of Pediatrics, Seoul National University, College of Medicine, Seoul, Korea
2Department of Neurosurgery, Seoul National University, College of Medicine, Seoul, Korea
3Department of Diagnostic Radiology, Seoul National University, College of Medicine, Seoul, Korea
4Department of Pathology, Seoul National University, College of Medicine, Seoul, Korea
5Department of Parasitology, College of Medicine, Chung-Ang University, Seoul, Korea
소아기에 발생한 중추신경계 낭미충증
박혜정1, 장성희1, 황세희1, 손재일1, 황용승1, 왕규창2, 조병규2, 김인원3, 연경모3, 지제근4, 조승열5
1서울대학교 의과대학 소아과학교실
2서울대학교 의과대학 신경외과학교실
3서울대학교 의과대학 진단방사선과학교실
4서울대학교 의과대학 병리과학교실
5중앙대학교 의과대학 기생충학교실
Received: 29 September 1990   • Accepted: 9 November 1990
A clinical study was performed on 5 patients of neurocysticercosis in childhood who admitted to the Seoul National University Hospital for the last two years. The conclusions were as follows: 1) Boys were more than girls with the ratio of 4:1. The average age was 9.5. 2) Three out of five lived in Jeju Island. Three had familial history of taeniasis. 3) Three out of five were diagnosed as ventricular cysticercosis and the other two as meningeal cysticer- cosis. 4) Main symptoms were those of IICP or chronic recurrent meningitis. 5) In all cases ELISA revealed the elevated level of Cysticercus-specific antibody in paired samples of serum and CSF and the titer of the la竹er was higher than that of the former. Two cases out of three which showed strong positive were meningeal cysticercosis. 6) Brain CT showed hydrocephalus and suggestive findings of intraventricular cysts. 7) Brain MRI showed hydrocephalus, intraventricular cysts and leptomeningeal enhancement. 8) One case of the 4th ventricular cysticercosis improved with cyst removal and praziquantel medication. Two of the meningeal cysticercosis and one of the lateral and 3rd ventricular cysticercosis improved with praziquantel only. 9) The average length of follow-up was 2.8 months. Although there was no evidence of recurrence in the course of follow-up, the longterm observation will be necessary to judge whether or not they cure completely. 10) Essential to eradication is prevention: sanitary diet, personal hygiene and environmental improvement.
Key Words: Neurocysticercosis

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