| Mannitol induced acute oliguric renal failure. |
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Young Mi Chung, Jae Seung Lee, Chang Jun Coe |
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Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea |
| Mannitol에 의한 핍뇨성 급성 신부전 1례 |
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정영미, 이재승, 고창준 |
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연세대학교 의과대학 소아과학교실 |
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Received: 8 February 1991 • Accepted: 11 March 1991 |
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| Abstract |
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Mannitol known as non-electrolytic, osmotic diuretic agent is widely used in clinic for the purpose
of diagnosis and prevention of acute oliguric renal failure, cerebral edema as well as glaucoma and
dialysis-disequilibrium syndrome. That mannitol may cause serious life-threatening situation if
administered in a patient with renal problem has been well known. Recently, it has been published
that mannitol may be nephrotoxic in patient without preexisting nephrologic disorder. We experi-
enced a case of acute oliguric renal failure in a patient with bacterial meningitis who had been treated
with high dose of mannitol to reduce intracranial pressure. This patient did not have any preexisting
renal problem, and the renal failure was successfully treated by peritoneal dialysis.
We are reporting this unusual clinical experience with recent literature review. |
| Key Words:
Mannitol, Acute renal failure |
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