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A clinical study on neonatal bacterial meningitis.

Journal of the Korean Pediatric Society 1991;34(6):763-770.
Published online June 30, 1991.
A clinical study on neonatal bacterial meningitis.
Yong Won Park, Jung Hwan Choi, Chong Ku Yun
Department of Pediatrics, Seoul National University, College of Medicine, Seoul, Korea
신생아 세균성 뇌막염의 임상적 연구 - 합병증 및 치료를 중심으로 -
박용원, 최중환, 윤종구
서울대학교 의과대학 소아과학교실
Received: 28 January 1991   • Accepted: 7 February 1991
Clinical courses of 12 neonates who were confirmed as neonatal bacterial meningitis by CSF culture or CSF latex agglutination test from January, 1986 to June, 1990, emphasizing on their complications and treatments, were evaluated. The results were summarized as follows; 1) The most common etiologic organism was E. coli (33.3%). 2) Two most common complications were ventriculitis (66.7%) and hydrocephalus (66.7%). 3) EVD with intraventricular antibiotics therapy was only performed in a half of patients with Gram(—) organism induced meningitis, and V-P shunt was needed in a half of patients with hydroce- phalus. 4) The prognosis was good in all patients with Gram(+) organisms induced meningitis, but poor in 4 cases (57.1%) among 7 patients with Gram(—) organisms induced meningitis. The prognosis was good in 4 cases who were not accompanied by ventriculitis and hydrocephalus, but poor in 4 cases (57.1%) among 7 cases accompanied by them.
Key Words: Neonate, Bacterial meningitis, Complication, Ventriculitis

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