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Clinical analysis and prognostic factors in Henoch-Schonlein purpura .

Journal of the Korean Pediatric Society 1991;34(5):682-690.
Published online May 31, 1991.
Clinical analysis and prognostic factors in Henoch-Schonlein purpura .
Ha Young Lee, Chong Sung Chung, Kyu Chul Choeh, Byoung Soo Cho, Young Mook Choi, Chang Il Ahn
Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, Korea
아나필락시스양 자반증의 임상적 고찰 및 예후인자 조사
이하영, 정종성, 최규철, 조병수, 최용묵, 안창일
경희대학교 의과대학 소아과학교실
Received: 4 September 1990   • Accepted: 31 January 1991
Abstract
This study was undertaken to evaluate the prognostic factors of recurrence and renal involvement in Henoch-Sch公nlein purpura. Total 110 cases of anaphylactoid purpura below 15 years of age who admitted to Pediatric Departmen of Kyung Hee University for 8 years from January 1st 1979 to December 31st 1986 were analyzed clinically and statistically. The results were obtained as follows. 1) The peak incidence of age was 4 〜6 years. 2) Ratio of male to female was 1.3:1. 3) Clinical manifestations: Skin & subcutaneous manifestation: 96(87.2%) Gastrointestinal manifestation : 57(51.8%) Joint involvement : 32(29.0%) Renal involvement : 31(29.0%) 4) Recurrence rate was 19.1% (21 cases). 5) Risk factors in recurrence: 1. Duration of symptoms before admission was 5 or less days. 2. Platelet count on admission was over 350,000/mm. 3. Gastrointestinal manifestation on admission. 6) Poor prognostic factors of renal involvement: 1. Duration of hospitalization was over 10 days. 2. Renal manifestation of admission. 7) Following factors on admission were evaluated for serching prognostic factors, but they were not significant. Clinical manifestations: 1. Age & aex 2. URI history 3. Skin & subcutaneous manifestation 4. Joint involvement manifestation 5. Renal involvement manifestation 6. Gastrointestinal manifestation 7. Duration of hospitalization 8. Duration of symptom before admission Laboratory findings 1. Hemoglobin 2. WBC count 3. MCV, MCH, MCHC 4. Platelet count 5. C3,C4 6. IgG, A, M
Key Words: Henoch-Sch*nlein purpura, Prognostic factors


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