| Adrenocortical carcinoma in a twelve month old male infant. |
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Woo Ryoung Lee, Kyoung Whan Oh, Chang Hwi Kim, Sang Jhoo Lee |
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Department of Pediatrics, College of Medicine, Soon Chun Hyang University, Seoul, Korea |
| 소아 부신피질 종양 1례* |
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이우령, 오경환, 김창휘, 이상주 |
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순천향대학 의학부 소아과학교실 |
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Received: 28 June 1990 • Accepted: 28 September 1990 |
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| Abstract |
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Adrenocortical carcinoma is a rare disease in childhood. Most of these carcinomas are functional, produc-
ing endocrine abnormalities such as Cushing syndrome, virilization, precocious puberty, hyperaldosteronism
or feminization.
We experienced a case of adrenocortical carcinoma in a 12 month old male infant who exhibited features
of Cushing syndrome, Virilization, precocious puberty and hyperaldosteronism, which were due to functional
adrenocortical carcinoma. Microscopic examination revealed cellular pleomorphism and bizzare multinu-
cleated nuclei. He was successfully treated by total left adrenalectomy and has been followed up without
problem over 13 months. A review of literatures was also made. |
| Key Words:
Adrenocortical carcinoma, Cushing syndrome, Vilirization, Precocious puberty |
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