Osteogenic Sarcoma as Second Malignant Neoplasm After Treatment of Retinoblastoma. |
Ja Young Kim, Moon Whan Lee, Ju Hyung Kim, Pyoung Han Hwang, Jung Soo Kim |
Department of Pediatrics, College of Medicine, Chonbuk National University, Chonju, Korea |
망막아세포종 치료후 이차성 종양으로 발생한 골육종 1례 |
김자영, 이문환, 김주형, 황평한, 김정수 |
전북대학교 의과대학 소아과학교실 |
Received: 5 July 1990 • Accepted: 28 September 1990 |
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Abstract |
The improvement in survival for childhood cancer has been achieved through the use of multiple-
agent chemotherapy and radiotherapy. However, one of the limitations to quality and length of
survival has been the development of second malignant neoplasm.
We exprienced a case of second malignant neoplasm in 13-year-old boy who developed osteogenic
sarcoma after successful treatment of retinoblastoma. At 3 years of his age, he was diagnosed as
retinoblastoma and managed by enucleation of left eye at a university hospital in Seoul. Ten years
later, painful swelling was noted on the right ankle joint. Histopathological findings revealed
osteblastic osteogenic sarcoma and metastasis to lung was detected on chest X-ray. He received
multiple-agent chemotherapy for one time. Thereafter, he was lost to follow-up and expired 9 months
after diagnosis of second mailgnant neoplasm. |
Key Words:
Second malignant neoplasm, Osteogenic sarcoma, Retinoblastoma |
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