| A Case of Diabetic Ketoacidosis Associated with Acute Lymphocytic Leukemia during Remission Induction Chemotherapy. |
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Gyu Jin Oh, Hwa Jeong Lee, Heui Jeong Kwon, In Sil Lee |
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Department of Pediatrics, National Police Hospital, Seoul, Korea |
| 급성 림프구성 백혈병환자의 완해유도 치료시 병발된
당뇨병성 케톤산증 1례 |
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오규진, 이화정, 권희정, 이인실 |
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국립경찰병원소아과 |
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Received: 30 June 1990 • Accepted: 4 September 1990 |
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| Abstract |
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L-asparaginase is known as an effective anticancer drug in the induction chemotherapy of acute
lymphocytic leukemia. The side effects or toxicities of L-asparaginase are hypersensitivity reaction,
hepatotoxicity, pancreatitis, transient diabetes mellitus, CNS toxicity, disorders of coagulation
system and mild cytotoxicity. We report a female patient with acute lymphocytic leukemia develop-
ing diabetic ketoacidosis during induction chemotherapy with L-asparaginase, parednisolone, vincris-
tine and intrathecal methotrexate, who died suddenly.
A brief review of literature was made. |
| Key Words:
Acute lymphocytic leukemia, L-asparaginase, Diabetic ketoacidosis |
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