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Relationship between anaphylactoid purpura and Beta-Hemolytic Streptococcal Infection.

Journal of the Korean Pediatric Society 1990;33(9):1231-1236.
Published online September 30, 1990.
Relationship between anaphylactoid purpura and Beta-Hemolytic Streptococcal Infection.
Ji Eun Lee, Young Sook Kang, Joon Sik Kim, Sung Ho Kim, Chin Moo Kang
Department of Pediatrics, School of Medicine, Keimyung University, Taegu, Korea
알레르기성 자반증과 β-용혈성 연쇄상구균 감염과의 관계*
이지은, 강영숙, 김준식, 김성호, 강진무
계명대학교 의과대학 소아과학교실
Received: 25 May 1990   • Accepted: 31 July 1990
Abstract
Relationship between anaphylactoid purpura and beta-hemolytic streptococcal infection was obser- ved and analyzed through clinical manifestation and labortory findings in 146 cases of allergic purpura, hospitalized at Dongsan hospital, Keimyung University during the period from January, 1981 to May, 1987. The following results were obtained. 1) The age distribution of anaphylactoid purpura showed a peak incidence between 2 to 7 years of age and male preponderance was observed with male to female ratio of 1.6 to 1. 2) The disease were found mostly in March and April(23.9%), also in October and November (23. 2%). 3) The clinical manifestations showed in skin (100%),gastrointestinal tract (73.2%), joint (61.6%), kidney (30.1%) respectively. 4) The preceding illness was shown in 29.5% of the cases and respiratory tract infections were more prevalent, noted in 22.5%. 5) As for the laboratory finding, Ig A was increased in 54.2% of cases, Ig E in 39.2% and eosinophil count in 14.3% and C3 level was decreased in 3.4% of cases. 6) ASO titer (over 333 todd unit) was elevated in 23.4% of the cases and beta-hemolytic streptococci was found in one case (0.7%) for throat culture. 7) Elevation of ASO titer was present in 25% of the cases who had renal involvement. The results obtained in this study hardly support a causal relationship between anaphylactoid prupura and the beta-hemolytic streptococcal infection.
Key Words: Anaphylactoid purpura, Beta-hemolytic streptococcal infection


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