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Human Rotavirus Antigen in Respiratory Secretion.

Journal of the Korean Pediatric Society 1990;33(9):1223-1230.
Published online September 30, 1990.
Human Rotavirus Antigen in Respiratory Secretion.
Kyung Min Lee, Won Chul Lee, Kook Shin Chang, Mee Kyung Chjang, Woo Tack Kim, Dong Jin Lee
Department of Pediatrics, Ulsan Dong-Kang Hospital, Ulsan, Korea
호흡기 분비물의 Human Rotavirus항원 검출에 대하여
이경민, 이원철, 장국신, 장미경, 김우택, 이동진
울산 동강병원 소아과
Received: 29 January 1990   • Accepted: 31 March 1990
Abstract
A clinical study was carried out on 33 diarrhea patients to determine the frequency and degree of respiratory symptoms and signs in patients with gastroenteritis who had HRV antigen in respira- tory secretion. We devided study group into two: One was 11 children who had HRV antigen in respiratory secretion but did not have in diarrheal stool and the other was 22 children who had HRV antigen in respiratory secretion and diarrheal stool both. Control group was 34 children who had HRV antigen in diarrheal stool but hadn’t in respiratory secretion. The HRV antigen was determined by latex agglutination test. All patients included in this study were admitted to the pediatric department of Ulsan Dong-Kang Hospital from November, 1988 to January, 1989. The following results were obtained; 1) There was no significant difference in age distribution, sex ratio, duration from onset of illness to admission and duration of hospital admission between study group and control one. 2) Coughing & rhinitis were noted on admission in two study groups 100% & 72.7% respectively, which were higher than those of control group(p<0.005). Wheezing, rhonchi, stridor & rale were noted on admission in two study groups 45.5% & 40.9% respectively, which were higher than those of control groups(p<0.005). 3) Duration of coughing in two study groups was 15.2 % ± 7.3 days & 12.1 % ± 5.8days respectively, which was longer than those of control group(p<0.00). Duration of rhinitis in two study groups was 13.1±3.1 days & 11.4±4.3 days respectively, which was also longer than those of control group(p< 0.005). 4) Duration of diarrhea in two study groups was 8.9±4.6 days & 7.5±3.3 days respectively, which was longer than those of control groups(p<0.05). 5) Out of associated illness & complication, bronchiolitis in two study groups was 36.4% both, pneumonia was 36.4% & 13.6% each other respectively, which were higher than those of control group(p< 0.001). 6) There was no significant difference in the tate of pulmonary infiltration on chest X-ray between study & control one.
Key Words: Human rotavirus antigen, Respiratory secretion


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