| Measurement of Carboxyhemoglobin in the Newborns with ABO Incompatible Hyperbilirubinemia. |
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Jung Ae Shin1, Son Moon Shin1, Jeong Ok Hah1, Chun Dong Kim2 |
1Department of Pediatrics, College of Medicine, Yeungnam University, Daegu, Korea
2Department of Pediatrics, Soon Chun Hyang Gumi Hospital, Gumi, Korea |
| ABO 부적합 신생아에서 과빌리루빈혈증의 발생과
Carboxyhemoglobin과의 관계 |
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신정애1, 신손문1, 하정옥1, 김춘동2 |
1영남대학교 의과대학 소아과학교실
2순천향 구미병원 소아과 |
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Received: 15 March 1990 • Accepted: 11 June 1990 |
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| Abstract |
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To develop more reliable screening test for ABO incompatible hemolytic disease than commonly
employed and to identify possible indicators of severity of hyperbilirubinemia, a pilot study was
performed by measuring the carboxyhemoglobin (HbCO) of the newborn babies within 48 hours after
birth. Forty eight newborn babies were studied and carboxyhemoglobin was measured by spectro-
photometry and serum bilirubin was measured by Diazo coupling method.
There were significant differences of HbCO levels between hyperbilirubinemic group with ABO
incompatibility and nonhyperbilirubinemic group with ABO incompatibility (1.17±0.77% vs 0.43±0.
23%) (p<0.05).
There were no significant differences of HbCO levels between hyperbilirubinemic newborns and
nonhyperbilirubinemic newborns of ABO compatible group (0.44±0.25% vs 0.36±0.17%).
Therefore measurement of HbCO within 48 hours after birth was considered to be useful for
prediction of hyperbilirubinemia in ABO incompatible newborn babies and it is necessary to monitor
bilirubin levels in such newborn babies during first few days of life |
| Key Words:
ABO incompatibility, Hyperbilirubinemia, Carboxyhemoglobin |
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