| A Study of Clinical Observations in Neonatal Sepsis. |
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E S Kim, K H Kim |
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Department of Pediatrics, College of Medicine, Ewha University, Seoul, Korea |
| 신생아 패혈층에 대한 임상적 고찰 |
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김은선, 김경희 |
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이화여자대학교 의과대학 소아과학교실 |
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Received: 20 March 1990 • Accepted: 16 June 1990 |
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| Abstract |
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We have experienced 67 cases of neonatal sepsis confirmed by clinical symptoms and blood culture
between July 1983 and June 1988 at Ewha university hospital.
The results obtained were as follows:
1) The incidence of septicemia was 0.6%. The sex ratio of patients was 0.97:1 with 33 males and 34
females.
2) The incidence was higher in preterm babies than in full term babies and higher in low birth
weight infant below 2.5 kg.
3) The incidence between early onset type and late onset type was not significantly different. The
mean age of onset was 6.8 days.
4) Among the perinatal complication, birth asphyxia and spontaneous premature rupture of
membrane were most commonly associated.
5) Among the concurrent conditions, the congenital anomaly was seen in 14 cases (20.9%) and it
was the highest incidence, metabolic disorders in 12 cases (17.9%). The hyaline membrane disease and
intraventricular hemorrhage were also presented in 5 cases and 3 cases, respectively.
6) Among the associated focal infections, the pneumonia and urinary tract infection were most
common.
7) Of the 67 cases with neonatal sepsis, the following causative organisms were isolated; Gram
positive organisms in 51 cases (76.1%), gram negative organisms in 14 cases (20.9%) and more than
two strains of bacteria in 2 cases (3.0%). Among these, staphylococcus aureus was the most common.
8) The significant diagnostic laboratory findings for septicemia were leukopenia «5,000/mm3),
neutrophil index (^0.2), thrombocytopenia «100,000/mm3), ESR^15mm/hr and CRP^1+.
9) The case mortality-rate was 6.0%. It was higher in mixed infections than in infections of single
organism. |
| Key Words:
Neonatal Sepsis |
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