| A Clinical Study on Tumors in Children. |
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Jae Wook Ko, Seon Wha Kim, Don Hee Ahn, Keun Chan Sohn |
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Department of Pediatrics, National Medical Center, Seoul, Korea |
| 소아 종양의 임상적 관찰 |
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고재욱, 김순화, 안돈희, 손근찬 |
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국립의료원 소아과 |
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Received: 29 November 1989 • Accepted: 23 February 1990 |
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| Abstract |
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A clinical study was made on 558 cases of benign or malignant tumors occuring under the age of
16 years which had been observed at the National Medical Center during a period of 12 years, from
January 1976 to December 1987.
Five hundred fifty eight tumors were divided into 308 benign, 223 malignant and 27 uncertain
tumors.
The frequency of malignant tumors among total admitted cases of pediatric department, was 0.9%.
Both Benign and malignant tumors showed the highest distribution in the age group of 0 to 5 years.
Leukemia were the most commonly observed in the age group of 0 to 5 years and 95% of bone and
cartilage tumors were distributed over the age 11. Most of retinoblastoma, neuroblastoma, hepatob-
lastoma were distributed under the age of 6.
The male to female ratio was 1.1:1 in benign tumors and was 1.6:1 in malignant tumors.
According to the organ or system of tumors, hemangioma of any site showed the highest frequency
in benign tumors. And bone & cartilage, lymphangioma of any site and genitourinary system were
next in the order of frequentcy. In malignant tumors the most frequent was hematopoietic system
followed by genitourinary, central nervous system and bone & cartilage in the order of frequency.
The most common malignant tumor was leukemia comprising 39.9% with 89 cases followed by
lymphoma, brain tumors and bone & cartilage tumors in the order of frequency.
Cases with distant metastasis on diagnosis were 24 (10.8%) in malignant tumors. Among 206 cases
of malignant tumors with available records, 126 cases were lost during follow-up regardless of
doctor’s opinion. The major causes of loss were nonappearance within reason, poverty and refusal to
treat. Over 90% of loss were occurred within 6 months from diagnosis.
Among 80 cases with adequate follow-up, 49 cases (61.3%) were dead, and 22 cases (27.2%) were
cured or under state of off-therapy. |
| Key Words:
Tumors in Children |
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