A Clinical Study on Reye's Syndrome. |
Myeong Hee Cha, Seong Hee Shin |
Department of Pediatrics, Pusan Adventist Hospital, Pusan, Korea |
Reye 증후군에 대한 임상적 연구 |
차명희, 신성희 |
부산위생병원 소아과 |
Received: 28 September 1989 • Accepted: 30 December 1989 |
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Abstract |
The auther analyzed the clinical features and prognosis of the 143 patients with Reye*s syndrome
who were admitted at three hospital for 10 years from Jan. 1979 to Dec. 1988.
The results were summarized as follows:
1) There was non significant difference in annual and seasonal incidence except slight higher
incidence in 1981.
2) The male to female ratio was 1.4:1. The age distribution was from 3 months to 10 years, and
most of the cases (81.2%) were under 3 years. The overall mortality rate was higher.
3) The prodromal illness were upper respiratory infection (65.7%), gastroenteritis and chickenpox.
4) The main clinical symptoms at admission were loss of consciousness (94.4%), nausea and
vomiting (86.7%), convulsion (60.8%), hepatomegaly, fever, and hyperpnea.
5) According to the severity (Lovejoy’s classification), the 59.4% of cases were in Stage or above
on admission and the cases were increased to 76.4% during admission.
The mortality rate was 36.4% and most of death were within 72 hours from admission. The higher
the stage, the higher the mortality rate. |
Key Words:
Reye’s syndrome |
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