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A Case of Patient with Common Variable Immunodeficiency.

Journal of the Korean Pediatric Society 1989;32(8):1123-1127.
Published online August 31, 1989.
A Case of Patient with Common Variable Immunodeficiency.
Keun Cheon Kim, Chang Gee Kang, Chang Hyun Yang, Dong Soo Kim, Kir Young Kim
Department of Pediatrics, Yonsei University, College of Medicine, Seoul, Korea
분류 불능형 면역 부전증 1례
김금전, 강창기, 양창현, 김동수, 김길영
연세대학교 의과대학 소아과학교실
Received: 25 January 1989   • Accepted: 24 March 1989
Abstract
Common variable immunodeficiency, as defined by World Health Organization classification of primary immunodeficiency, is a heterogenous group of disorders with hypogammaglobulinemia, decreased ability to produced antibody following antigenic challenge, and increased incidence of infections. The disorder was often familial, but no mode of inheritance has been discerned. Clinical fingings are recurrent bacterial infections, particularly respiratory infection. Laboratory evaluations in common variable immunodeficiency demonstrate decrease in th serum concentration of all major immunglobulin classes, IgG, IgM and IgA. T cell number and function may be abnormal and the ratio of T helper cell to T suppressor cell is reversed. We experienced a case of common variable immunodeficiency in a 7 year old boy who was admitted due to septic arthritis in left shoulder. This boy had typical clinical and labaratory features of common variable immunodeficiency. This case was discussed with a review of the literatures.
Key Words: Common Variable Immunodeficiency


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