| A Case of Acute Megakaryoblastic Leukemia in Infant with Down's Syndrome. |
|
Jung Soon Whang1, Soon hee Kim1, Moon Ja Kim1, Keun Lee1, Je Geun Chi2 |
1Department of Pediatrics, College of Medicine, Ewha Womans University, Seoul, Korea
2Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea |
| Down 증후군과 동반된 급성거핵아구성
백혈병 1례 |
|
황정순1, 김순희1, 김문자1, 이근1, 지제근2 |
1이화여자대학교 의과대학 소아과학교실
2서울대학교 의과대학 병리학교실 |
|
Received: 30 October 1987 • Accepted: 16 March 1988 |
|
|
| Abstract |
|
Acute megakaryoblastic leukemia is an uncommonly recognized disorder that is characterized by
rapidly progressive proliferation of atypical megakaryocytes and their precursor cells, and fatal
course. Abnormalities in chromosome 21 may have a more than random relationship to acute
megakaryoblastic leukemia.
The authors reports a case of acute megakaryoblastic leukemia in a 2 month old female patient
who was admitted for evaluation of hepatosplenomgaly.
Multiple organ infiltration of atypical megakaryocytes were confirmed on autopsy. The
chromosomal analysis revealed 21 trisomy. |
| Key Words:
Acute Megakaryoblastic Leukemia, Down’s Syndrome |
|
PDF Links
Download Citation
