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Doppler Echocardiographic Determination of the Time of Ductal Closure in Normal Newborn Infants.

Journal of the Korean Pediatric Society 1988;31(6):747-753.
Published online June 30, 1988.
Doppler Echocardiographic Determination of the Time of Ductal Closure in Normal Newborn Infants.
Dong Joo Na1, Hyung Kook Kim1, Jong Wan Kim1, Sang Min seong1, Kyong Su Lee1, In Soo Park2
1Department of Pediatrics, Catholic University Medical College, Seoul, Korea
2Department of Internal Medicine, Catholic University Medical College, Seoul, Korea
도플러 심장초음파를 이용한 정상신생아의 동맥관 폐쇄시기 측정
나동주1, 김형국1, 김종완1, 성상민1, 이경수1, 박인수2
1가톨릭대학 의학부 소아과학교실
2가톨릭대학 의학부 내과학교실
Received: 27 August 1987   • Accepted: 1 February 1988
Abstract
Pulsed Doppler echocardiography, a sensitive and specific non-invasive method enabled the various congenital and acquired heart diseases to be detected sine 1970,s For determining the time of functional closure of ductus arteriosus, 30 normal newborn infants were examined by pulsed wave Doppler (PWD) from March 1 to April 30, 1987, in Holy Family Hospital, Catholic Medical Center. A PDA was diagnosed when abnormal diastolic ductal flow into MPA could be recorded using PWD. All newborn infants were initially examined within 6 hours of age and following examinations were performed twice daily thereafter until PDA evidence could be no longer detected. The M-mode echocardiographic measurements were taken at the initial and final examination to evaluate the ductal shunts. In 93.3% (28/30) of newborn infants, PDA was detected on the initial examination. Of these cases, PDA was no longer to be detected in 73.3% by 24 hours of age, in 86.6% by 48 hours, in 93.3% by 72 hours and in all by 96 hours of age. There were no M-mode echocardiographic evidences for a significant left to right shunt of PDA in any cases. There was no clear association between the time of functional closure of PDA and birth weight, sex difference, delivery type. These data indicate that ductal patency is common in the normal newborn infants, and that the functional closure of PDA may not occur until later than previously belived.
Key Words: Patent ductus arteriosus, Pulsed wave Doppler, Main pulmonary artery, Ductus arteriosus


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