| A Case of Pulmonary Candidiasis. |
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Hye Ran Byun1, Kung Ha Ryu1, Moon Ja Kim1, Keun Lee1, Yeon Lim Suh2, Je Geun Chi2 |
1Department of Pediatrics, College of Medicine, Ewha Womans University, Seoul, Korea
2Department of Pathology, College of Medicine, Seoul National University, Seoul, Korea |
| 폐 칸디다증 1례 |
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변혜란1, 유경하1, 김문자1, 이근1, 서연림2, 지제근2 |
1이화대학교 의과대학 소아과학교실
2서울대학교 의과대학 병리학교실 |
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Received: 23 September 1987 • Accepted: 23 December 1987 |
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| Abstract |
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A case of fatal pulmonary candidiasis was diagnosed at autopsy of 5-month-old female infant.
Patient had mild coughing, poor weight gain and marked hepatosplenomegaly. She had no sign of
immune dysfunction but developed fever, wheezing and intermittent respiratory distress. Chest P-A
showed infiltrations of multiple lobar pneumonia. Postmortem examination revealed the whitish
necrotic mass like lesion with a feature of lobar pneumonic consolidation in the right lung and the
upper lobe of the left lung. There were numerous small cystic spaces mimiking a honeycomb scattered
within the necrotic lesion. Microscopically the lesions consisted of exuberant necrotizing granulomas
and fibrosis. Periodic acid-Schiff and Methenamine Silver stains showed small numbers of round to
oval shaped, yeast like organisms mixed with pseudohyphae in the necrotic center of the granulomas.
The liver was markedly enlarged and showed early cirrhotic change of micronodular type, together
with acinar arrangement of hepatocytes and bile plugging, and cholestasis. |
| Key Words:
Pulmonary candidiasis |
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