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A Clinical Review of Congenital Anomalies in Neonates.

Journal of the Korean Pediatric Society 1988;31(3):306-314.
Published online March 31, 1988.
A Clinical Review of Congenital Anomalies in Neonates.
Chan Gyoo Hwang, Byung Ho Lim, Ki Bok Kim
Department of Pediatrics, Kwangju Christian Hospital, Kwangju, Korea
출산아의 선천성 기형에 대한 임상적 고찰
황찬규, 임병호, 김기복
광주기독병원 소아과
Received: 10 November 1987
Abstract
A study was made on the incidence of malformation among 8959 babies delivered at Kwangju Christian Hospital during a period of three years starting from June 1983. The results are summarized as follows: 1) Of 8959 newborns 243 babies (2.7%) were found to have some form of malformation. The incidence was 3.0% for male and 2.3% for female, but no significant difference between both sexes was noted. 2) Of 789 low-birth-weight infants, 39 (4.9%) were malformed, wherease among 8170 full-term infants 204 babies (2.5%) had malformations, indicating that low-birth-weight infants have hgiher incidence of malformation (P<0.01). 3) Theincidence of malformation was not related with the number of parity (P<0.1). 4) Among 8796 liver-bom infants, 232 (2.6%) had malformations, wherease 11 (6.7%) were found anomalous among 163 still-bom babies, revealing significantly higher incidence in the la竹er group (P<0.01). 5) 2.7% of babies bom to mothers younger than 35 years of age had malformations, wherease mothers older than 35 years delivered anomalous babies in 3.2%, but there was no significant difference between both groups (P>0.1). 6) The incidence of malformation seems to be related to the length of gestational period, as 4.1% of babies who had bad a gestational period less than 38 weeks had malformations, while 2.6% of infants who had had a gestation longer than 38 weeks were malformed (P<0.05). 7) Of 243 malformed babies 29 (11.9%) had multiple malformation, most commonly involving two separate organs. The organs involved were in descending order of frequency: the musculoskeletal, gastrointestinal, cutaneous, genitourinary, cardiovascular, central nervous, and the respiratory sys- tem. 8) Classified according to Marden, the severe form, with 1,95%, predominate over the mile form (1.35%). 9) Twenty six of the malformed infants (10.7%) were either stillborn or dead on delivery, and anencephaly was the most common malformation among them.
Key Words: Congenital Malformations


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