| A Clinical Review of Congenital Anomalies in Neonates. |
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Chan Gyoo Hwang, Byung Ho Lim, Ki Bok Kim |
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Department of Pediatrics, Kwangju Christian Hospital, Kwangju, Korea |
| 출산아의 선천성 기형에 대한 임상적 고찰 |
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황찬규, 임병호, 김기복 |
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광주기독병원 소아과 |
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Received: 10 November 1987 |
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| Abstract |
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A study was made on the incidence of malformation among 8959 babies delivered at Kwangju
Christian Hospital during a period of three years starting from June 1983. The results are summarized
as follows:
1) Of 8959 newborns 243 babies (2.7%) were found to have some form of malformation. The
incidence was 3.0% for male and 2.3% for female, but no significant difference between both sexes
was noted.
2) Of 789 low-birth-weight infants, 39 (4.9%) were malformed, wherease among 8170 full-term
infants 204 babies (2.5%) had malformations, indicating that low-birth-weight infants have hgiher
incidence of malformation (P<0.01).
3) Theincidence of malformation was not related with the number of parity (P<0.1).
4) Among 8796 liver-bom infants, 232 (2.6%) had malformations, wherease 11 (6.7%) were found
anomalous among 163 still-bom babies, revealing significantly higher incidence in the la竹er group
(P<0.01).
5) 2.7% of babies bom to mothers younger than 35 years of age had malformations, wherease
mothers older than 35 years delivered anomalous babies in 3.2%, but there was no significant
difference between both groups (P>0.1).
6) The incidence of malformation seems to be related to the length of gestational period, as 4.1%
of babies who had bad a gestational period less than 38 weeks had malformations, while 2.6% of
infants who had had a gestation longer than 38 weeks were malformed (P<0.05).
7) Of 243 malformed babies 29 (11.9%) had multiple malformation, most commonly involving two
separate organs. The organs involved were in descending order of frequency: the musculoskeletal,
gastrointestinal, cutaneous, genitourinary, cardiovascular, central nervous, and the respiratory sys-
tem.
8) Classified according to Marden, the severe form, with 1,95%, predominate over the mile form
(1.35%).
9) Twenty six of the malformed infants (10.7%) were either stillborn or dead on delivery, and
anencephaly was the most common malformation among them. |
| Key Words:
Congenital Malformations |
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