| A Case of Systemic Lupus Erythematosus Accompanied with Nephritis and Arteritis. |
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Oh Kyun Kwon, Hong Yang Khil, Jae Ho Lee, Young Hun Chung |
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Department of Pediatrics, College of Medicine, Chungnam National University |
| 전신성 홍반성 낭창 1례 |
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권오균, 길홍량, 이재호, 정용헌 |
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충남대학교 의과대학 소아과학교실 |
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| Abstract |
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The systemic lupus erythematosus (SLE) is a chronic inflammatory disease involving skin, kidney,
serous membrane, nervous system and other organs.
We experienced a case of SLE accompanied with nephritis and arteritis on the region of the left
thigh, diagnosed by clinical, serologic, immunologic, radiologic and pathologic evaluations.
A 15 years old female patient was admitted to pediatric ward due to sustained pain on left thigh.
She exhibited symmetric erythematous rashes on the face, intermittent moderate fever, enlarged
cervical lymphnodes and hepatosplenomegaly on admission. The hematologic findings revealed
anemia on peripheral blood and erythroid hyperplasia on bone marrow. The urine findings revealed
proteinuira, hematuria and granular casts. The results of ANA, LE, VDRL and Commbs’ test were
positive serologically and the level of C3 was 20 mg/dl. The femoral angiography showed decreased
vascularity, beading of the vascular wall and narrowed vascular lumen on left side. There were
massive granular deposits of the immune complex, complements and electron dense materials on
renal bipsy specimen compatible with diffuse proliferative lupus glomerulonephritis (WHO Class IV).
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| Key Words:
Systemic lupus erythematosus, Lupus nephritis, Vasculitis
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