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Paraquat Poisoning.

Journal of the Korean Pediatric Society 1987;30(8):891-900.
Published online August 31, 1987.
Paraquat Poisoning.
Soo Yup Lee, Jeh Hoon Shin, Woo Gill Lee
Department of Pediatrics, College of Medicine, Han Yang University Seoul, Korea
Paraquat 중독
이수엽, 신재훈, 이우길
한양대학교 의과대학 소아과학교실
Abstract
Paraquat is a widely used herbicide and in human its poisoning induces acute renal failure, hepatic dysfunction, progressive respiratory failure, and oral cavity ulcer etc. with high mortality rate of 30-70%. The authors analyzed twenty-one cases of paraquat poisoning who were admitted at Hanyang University Hospital from May, 1972 to December, 1986 and the results were as followings. 1) Among 21 cases, 11 cases were male and the rest were female, and therefore, sex ratio were 1.6 : 1. All cases were intoxicated by ingestion and cause of ingestion was primarily suicidal attempt (57.1%). 2) The major symptoms and signs were sore throat, oral cavity ulcer, dysphagia, dyspnea, epigas-tric pain or tenderness, jaundice, and nausea or vomiting. 3) The major laboratory abnormalities of most cases were proteinuria, elevations of BUN, creatinine, SGOT, SGPT and serum bilirubin, and lowerings of pH, PaCO2 and PaO2 in arterial blood gas analysis. 4) The mortality rate was 85.7% and main causes of death were respiratory failure (61.5%), acute renal failure (7.7%), and esophageal perforation (7.7%).
Key Words: Paraquat poisoning


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