| The Evaluation for the Immunotherapy to Bronchial Asthmatics. |
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Jung Woo Shin |
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Dept, of Pediatrics, College of Medicine, Pusan National University |
| 소아천식환자에 대한 면역요법의 평가 |
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신종우 |
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부산대학교 의과대학 소아과학교실 |
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| Abstract |
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The changes of skin-test reactivities, total and specific serum IgE levels, and peripheral eosinophil
counts were observed periodically in 20 bronchial asthmatics.
The immunotherapy was performed with the Specific desensitization Vaccine(Bencard), i. e.
mixture of multiple allergens specific for each patients, and scheduled reach the maintenance doses
within 6 months.
The skin-test reactivity index, i. e. the ratio of the average diameter of the wheal raised by
intradermal injection of allergen mixture to that of 0.1% histamine, showed no uniform changes
during the period.
The total serum IgE levels were measured by PRIST before immunotherapy, after 1 year’s and 18
months immunotherapy.
They showed decreasing tendency through the period.
All the specific IgE levels measured by RAST after 18 months of therapy showed either equal or
reduced levels compared with the initial levels.
The peripheral eosinophil counts checks after 18 months showed no noticeable changes.
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| Key Words:
Bronchial asmatics, Immunotherapy.
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