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A Case of Dubin-Johnson Syndrome in Childhood.

Journal of the Korean Pediatric Society 1986;29(11):1275-1280.
Published online November 30, 1986.
A Case of Dubin-Johnson Syndrome in Childhood.
Young Hoon Kim, Young Soo Kim, Sang Kyu Park, Jung Ki Seo, Yong Choi
Dept, of Pediatrics, College of Medicine, Seoul National University
Dubin-Johnson 증후군 1례
김영훈, 김영수, 박상규, 서정기, 최 용
서울대학교 의과대 학 소아과학교실
Abstract
A case of Dubin-Johnson syndrome in 10-year-old Korean male child was presented. The presenting symptom was dark-colored urine for several years. Laboratory findings showed increased bilirubin, especially direct-reacting bilirubin, and abnormal urinary coproporphyrin pattern (coproporphyrin I : 58%, coproporphyrin JK : 42%). Needle biopsy specimen of liver showed dark-brownish pigmentation in liver cells but was otherwise normal histologically.
Key Words: Dubin-Johnson syndrome.


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