Primary Hematuria in Children. |
Myung Chul Hyun, Geum Joo Kim, Kuhn Soo Lee, Ja Hoon Koo |
Department of Pediatrics、School of Medicine, Kyungpook National University, Taegu,Korea |
소아 알차성 혈뇨의 임상 및 병리학적 고찰 |
현명철, 김금주, 이건수, 구자훈 |
경북대학교 의과대학 소아과학교실 |
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Abstract |
A clinico-pathological observation was done on 23 children with primary hematuria, who had been admitted to the Pediatric ward of KNU Hospital from January 1981 to August 1985. All children were undergone percutaneous renal biopsy. The following resullts were obtained; Sex distribution showed male predominance with male to female ratio of 2.8:1 and 11 〜15 years of age group were the most frequently involved, comprising 52.2%, Pathologic findings showed minimal change in 14 & focal proliferative change in 5 cases (Group I), and focal sclerosis and/or capsular adhesion in 3 & membranous nephropathy in 1 case (Group H). 7 out of 15 cases in which immunofluorescent study was done showed prominant deposit of IgA in the glomerulus. However, this finding was not related with severity of the underlying renal pathology. Type of hematuria was recurrent gross in 18 and microscopic in 5 cases. Mild edema was noted in 7 cases and this was noted more frequently in Group II compared- to Group I (p<0.55). Serum IgA values were increased in 7 out of 13 tested cases. On urinalysis, persistant
proteinuria was noted more frequently in Group 고 than Group I (p<0.01). In summary, it can be concluded that the finding of mild edema and persistant proteinuria in a patient with primary hematuria indicates serious underlying renal pathology,
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Key Words:
Primary hematuria, IgA nephropathy. |
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