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Change of Pulmonary Function after Exercise Loading Test and Preventive Measures on Exercise-induced Asthma in Chlidren.

Journal of the Korean Pediatric Society 1986;29(3):277-286.
Published online March 31, 1986.
Change of Pulmonary Function after Exercise Loading Test and Preventive Measures on Exercise-induced Asthma in Chlidren.
Ki Yung Lee
Department of Pediatrics, College of Medicine, Yonsei University
運動誘發性端息患兒에 있어서 運動負荷試驗後 肺機能의變化와 豫防對策
李琦寧
延世大學校醫科大學小兒科學敎室
Abstract
143 cases(106 males, 37 females) with asthmatic children (aged from 54/i2 to 144/i2 year old) were performed pulmonary function test before and after exercise to detect exerciseinduced asthma (El A). If peak expiratory flow rate(PEFR), checked with Wright’s peak flowmeter, decreased 15% cr more after exercise loading test (up and down stair method for 6 minutes), the result was considered to be positive. 77 and 66 cases were confirmed as to have EIA and non-EIA repectively. The results were as follows; 1) Base line value of %PEFR(93.88%) was decreased markedly(58.89%) after exercise in EIA cases but minimal change of% PEFR, ranged from 89.49% to 93,47%, was noted after exercise in non-EIA cases. 2) Mean post-exercise decrease of % PEFR were 5.76% and 33.82% in non-EIA cases and EIA cases repectively. 3) Significant decrease of %PEFR was noted at 5 minutes after exercise in EIA cases (51.9%). 4) 55.8% of EIA cases could not return to base line value of PEFR untill 30 minutes post-exercise period. 5) 69.2% and 70.6% of EIA cases were effective to prevent EIA by the pretreatment with Tranilast and cromolyn respectively. It can be concluded that proper preventive measures should be given to EIA cases as early as possible because of markedly decreased pulmonary function after exercise.
Key Words: Exercise-induced asthma(EIA), Peak expiratory flow rate(PEFR), Exercise loading test, Base line value, Forced expiratory volume in 1 second (FEVi).


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