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A Clinical Study on Reye Syndrome.

Journal of the Korean Pediatric Society 1985;28(11):1089-1096.
Published online November 30, 1985.
A Clinical Study on Reye Syndrome.
Yong Hae Lee, Jong Chul Yu, Jun Taek Park, Chang Hee Choi
Dept, of Pediatrics, Seoul Adventist Hospital
Reye 증후군에 대한 임상적 고찰
이용해, 유종철, 박준택, 최창희
서울위생병원 소아과
Abstract
Fifty-five cases of Reye’s syndrome, diagnosed during the period of October 1 st, 1980-September 31st, 1984 at the Pediatric of Seoul Adventist Hospital, were studied on the clinical features and laboratory finding. The following results were obtained; 1)There was no much indifference in annual incidence but highest incidence was showed September by 9 cases (16.4%). 2)The sex ratio of male to female was 28 cases: 27 cases almost same level. 3)There was under 2 years 49 cases(89.1%) among 55 cases in age distribution, almost overall cases. 4)The prodromal illness was upper respiratory infection that was 30 cases among 5& cases distributing over the half cases, the other illness were gastroenteritis, chicken pox,measles, bronchiolitis. 5)The main clinical symptoms were disturbed consciousness (98.2%), vomiting(87.3%), fever(61.8%), convulsion(54.5%) and the others were cough(40%), hepatomegaly(50.9%) diarrhea(27.3%) Jaundiced. 8%). 6)According to Lovejoy' s classification, at the time of admission, the serious symptoms above stage JU were 23 cases(41.8%) among 55 cases. The higher the stage, the higher the mortality. 7)The higher the level of serum Ammonia, LDH, GOT, the higher the mortality. 8)The mortality rate was 36.4% by 19 cases among 55 cases.
Key Words: Reye's Syndrome


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