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A Clinical Study on Duchenne Muscular Dystrophy in Childhood.

Journal of the Korean Pediatric Society 1985;28(6):581-586.
Published online June 30, 1985.
A Clinical Study on Duchenne Muscular Dystrophy in Childhood.
Chung Il Noh, Yong Seung Hwang
Department of Pediatrics,College of Medicine,Seoul National University
소아기 Duchenne 형 근이 영양증에 대한 임상려 관찰
노정일, 황용승
서울대학교 의과대학 소아과학교실
Abstract
Twenty-six cases of Duchenne muscular dystrophy (DMD) who were diagnosed in the Department of Pediatrics, Seoul National University Hospital from Jan. 1976 till Jan. 1985 were reviewed. The onset of symptoms was between two and eleven years of age. The peak incidence was at 3 years of age. Both extremities were involved in 14 cases. The degree of involvement was not affected by onset age, admission age and the, duration of the disease before admission. Out of 18 cases examined, twelve cases were thought to be inherited, and six cases to be sporadic. Mental retardation was noticed in three ca^es. The most common change in ECG was Rsr' in V1. Other findings were, increased R% in V2, increased sum of R+S in V2, deep Q in V6, and high R in V6. Serum CPK and LDH level have no relation to the age of the patients.
Key Words: Duchenne muscular dystrophy


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