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Clinical trials of lactous free soy protein based formula for infantile diarrhea.

Journal of the Korean Pediatric Society 1985;28(5):463-469.
Published online May 31, 1985.
Clinical trials of lactous free soy protein based formula for infantile diarrhea.
Soon Wha Kim, Keun Chan Sohn
Department of Pediatrics, National Medical Center, Seoul, Korea
嬰幼兒泄瀉에서 國産 soy protein based formula의 臨床歎果에 對하여
金順華, 孫權贊
國立醫療院 小兒科
Abstract
We observed 50 infants admitted to the Dept, of Pediatrics, National Medical Center to determine the efficacy of lactose free soy protein based formula, domestic products, on the recovery of diarrhea from Sept. 1984 to Dec. 1984. Cases were divided into two groups, group 1 was consisted of 25 infants who were given lactose free soy protein formula, and group 2 was also consisted of 25 infants who were given milk formula during the recovery stage. We determined to compare with admission age, weight, duration of diarrhea, number of stools per day, hematocrit, electrolyte, BUN, stool pH, stool clini test and rota virus between group 1 and group 2. The results were as follows; 1)There was no difference between the two groups in age, but weight in group 1 was less than group 2. 2)There was no difference between the two groups in number of stools per day at admission, but duration of diarrhea in group 1 was longer than group 2. 3)There was no difference between the two groups in hematocrit, electrolite, and BUN. 4)All stool pH were below, 6.7 in both groups, and pH 5.4~5.8 were most common in both groups. Stool clini test above 0.5% was seen in 52% of groups 1 and 64% of group 2, 5)Rota virus positive rate was 58% in group 1 and 64% in group 2. 6)Frequency of diarrhea per day at admission was no difference in both groups, but after 3rd days, frequency much decreased in group 1 than group 2. 7)Suess rate was 84% (21 success and 4 failure) in group 1 and 60% (15 success and 10 failure) in group 2. This represented a significant success rate in group l(p<0.05). In summary, we believe our data favor the use of a soy based formula, domestic products, for the feeding of infants during the recovery phase of infantile diarrhea.
Key Words: Lactose free, Soy protein based formula, Infantile diarrhea


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