Warning: fopen(/home/virtual/pediatrics/journal/upload/ip_log/ip_log_2024-03.txt) [function.fopen]: failed to open stream: Permission denied in /home/virtual/pediatrics/journal/ip_info/view_data.php on line 82

Warning: fwrite(): supplied argument is not a valid stream resource in /home/virtual/pediatrics/journal/ip_info/view_data.php on line 83
Hepatitis B Serologic Markers at Birth in Babies of HBsAg-Positive Mothers.

Journal of the Korean Pediatric Society 1985;28(3):236-241.
Published online March 31, 1985.
Hepatitis B Serologic Markers at Birth in Babies of HBsAg-Positive Mothers.
Jeoung Wan Seo, Hye Seung Kim, Keun Lee
Department of Pediatrics, College of Medicine,Ewha Womans University
HBsAg 양성 모체에서 태어난 신생아에서의 B형간염바이러스 항원항체와 분포
서정완, 김혜승, 이근
이화여자대학교 의과대학 소아과학교실
Abstract
It has been established that hepatitis B virus may be transmitted from mothers to infants in the perinatal period. A study was undertaken to identify HBsAg in neonates born to mothers who were asymptomatic carriers of HBsAg. From Jan. 1 ’83 to June 30 ’84, total 4,044 cases of pregnant women and 131 babies were studied for serologic markers of hepatitis B virus in their sera by radioimmunoassay. Followings are the summary of the findings; 1)Screening of 4,044 pregnant women revealed that 190(4.7%) were HBsAg positive. Of 131 HBsAg-positive mothers, 57(43.5%) had HBeAg. 2)All 131 neonates of HBsAg-positive women were tested immediately after birth: In 4.6%(6 of 131), HBsAg was found in their sera. 3)HBsAg was detected in 4(7.01%) neonates born to 57 mothers who had HBsAg-positive and HBeAg-positive sera. And in 2(2.7%) neonates of 74 HBsAg-positive and HBeAg-nega- tive mothers, HBsAg was found. 4)One of the 49 infants(2.05%) born to HBsAg-positive and Anti-HBe positive mothers showed HBs-Antigenemia immediately after birth. 5)The presence of Anti-HBe, Anti-HBc and Anti-HBs in the sera of the neonates bornto HBsAg-positive mothers correlated with those of mothers.
Key Words: Hepatitis B serologic markers at birth, Transplacental transmission, Hepatitis B, Neonate


METRICS Graph View
  • 1,202 View
  • 11 Download