| The Effect of Antitoxin in Neonatal Tetanus. |
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Myung Dong Ahn, Tae Joo Whang, Chull Sohn |
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Faculty of Medical Science Chonnam University Graduate School |
| 신생아 파상풍에 대한 항독소의 치유효과 |
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안명동, 황태주, 손철 |
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전남대학교 의과대학 소아과학교실 |
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| Abstract |
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Mortality rate of Neonatal tetanus was assessed in 198 casss out of 219 patients during 10 years(1970~1979) according to the amounts of administered antitoxin dosages in a prospective and randomized trial.
Mortality rate of Neonatal tetanus administered antitoxin 10,000 I.U. averaged 64.2%, whereas that of Neonatal tetanus administered antitoxin 20,000, 40,000, 60,000 and 100,000 I.U. averaged 60.9%, 78.0 c, 57.1% and! 59.5%, respectively. However, no statistical differences in mortality rate among the dosage groups were observed.
This demonstration of no differences in mortality rate to the various amounts of antitoxin dosages does not seem to support the usage of large dose of antitoxin for routine treatment of Neonatal tetanus.
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| Key Words:
Neonatal tetanus, Antitoxin, Mortality rate. |
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