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Leukocyte Alkaline Phosphatase Activity in Children with leukocytosis.

Journal of the Korean Pediatric Society 1983;26(5):476-481.
Published online May 31, 1983.
Leukocyte Alkaline Phosphatase Activity in Children with leukocytosis.
Byung Giu Kim
Department of JPediatrics,Maryknoll Hospital
소아백혈구 증다증에 있어서 백혈구 Alkaline Phosphatase 활성
부산 메리놀병원 소아과
The leukocyte alkaline phosphatase activity in 43 children with leukocytosis who were admi竹ed to Busan National University and Busan Maryknoll Hospital from Oct. in 1980, to Mar. in 1981, was investigated histochemically with the Tomonaga’s naphtol AX-MX pho-sphate fast blue RR method. The results were summerized as follow. 1) The LAP activity in healthy children shows no variation in spite of difference in sex, age and neutrophil count. 2) The LAP activity scores of children with leukocytosis was higher than that of healthy children. In the children with leukocytosis, the higher the neutrophil count was the higher the LAP activity scores. 3) The LAP activity scores was higher in children with nonbacterial leukocytosis, and it was higher in the children with pneumonia and meningitisas compared with the children with tuberculosis. 4) Increased LAP activity in children with leukocytosis was returned to that of healthy children with the decreament of leukocyte counts to 5,000—10,000/mm3
Key Words: Leukocyte alkaline phosphatase, Leukocyte.

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