| A Study of Correlation between Bilirubin Leel of Cord Blood and Neonatal Hyperbilirubinemia. |
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Hwan Sup Kang, Chang Il Ahn |
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Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul，Korea |
| 제대혈 총빌리루빈치와 신생아 황달과의 관계 |
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강환섭, 안창일 |
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경희대학교 의과대학 소아과학교실 |
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| Abstract |
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For adequate management and prevention of severe sequellae of neonatal hyperbilirubinemia^
such as kernicterus, early detection of its presence is very important in fields of neonatology.
The author studied the correlation between bilirubin level of the cord blood and neonatal
hyperbilirubinemia in random sampled 169 neonates of 729 deliveries during a period of five
months since December 1981 at the Kyung Hee University Hospital. The blood groups and
types (ABO, Rh) of both neonates and mothers, hemoglobin, hematocrit, and reticulocyte
values of the cord blood were determined, and direct Coombs' tests were performed in neon-
ates with documented hyperbilirubinemia.
The results were obtained as follows:
1. The total cord bilirubin level of the 169 neonates averaged 1.42+0.40mg/dl, while that
of ABO incompatibility group 5.17±3.89mg/dl, that of treated group 1.63±0.35mg/dl and
not treated 1.40±0.42mg/dl(Treated group: Not treated group = p<0.05).
2. Visible jaundice of the treated group ；appeared at 3.05±l. 35 days of life with total
serum bilirubin level of 10.92±1.94mg/dl and the highest level was noted at 4. 85±1.31days
of life with 16.49±1.78mg/dl.
3. The neonates who were managed for hyperbilirubinemia were 20 of 169(11.8%).Visible
jaundice of the jaundiced group appeared at third to fourth day of life(90%), and appeared
within 12 hours of life in three fourth of ABO incompatibility group.
4. The results obtained indicated that the determination of total bilirubin level, blood
grouping, and direct Coombs’ test of cord blood were valuable^for early detection of hyperbili
rubinemia in case of maternal “O” blood group having suspiciously ABO incompatibility with
neonates.
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| Key Words:
Hyperbilirubinemia, Cord blood, Neonatal Jaundice. |
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