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Two Cases of IgA Nephropathy.

Journal of the Korean Pediatric Society 1981;24(5):485-491.
Published online May 15, 1981.
Two Cases of IgA Nephropathy.
Ho Jin Lee1, Woon Sik Kim1, Don Hee Ahn1, Keun Chan Sohn1, Hyun Soon Lee2
1Department of Pediatrics, National Medical Center Seoul, Korea.
2Department of Pathology, Seoul National University, Medical College, Korea.
IgA 腎病症 2例
李昊鎭1, 金云植1, 安敦姬1, 孫權贊1, 李賢淳2
1國立醫療院 小兒科
2서울大學校 醫科大學 病理學敎室
Two cases of IgA nephropathy in an 11-year-old girl(Case I) and a 10-year-old boy(Case II) were presented. Case I, an 11-year-old schoolgirl, had recurrent painless hematuria of 6-month duration which began with URI symptoms at the onset. No edema was noted and urine volume was sufficient throughout the course. Mild proteinuria had been noted from time to time. Blood pressure was 140/90mmHg on admission but dropped soon to normal. Percutaneous renal biop-sy revealed proliferative focal glomerulosclerosis on light microscopy, IgA(+++) deposition in mesangium and subendothelium on immunofluorescent study, and election dense deposit in the mesangium on electron microscopy. Case II, a 10-year-old schoolboy, had suffered from symptomless hematuria of 3-month duration. The onset developed with skin infection, the 2nd relapse with otitis media and the 3rd with URI like symptoms. Other lab, findings were all within normal limit. Renal biopsy revealed minor change with segmental focal glomerulosclerosis on light microscopy, mesangial deposition of IgA(+++) & C3(+) on immunofluorescent study, and electron lense deposit in the mesangium on electron microscopy.
Key Words: Recurrent hematuria, focal glomerulonephritis, IgA nephropathy

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