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A Clinical Study of Wilms' Tumor with Special Reference to the Cure Rate by Multimodality Treatment.

Journal of the Korean Pediatric Society 1980;23(7):557-566.
Published online July 15, 1980.
A Clinical Study of Wilms' Tumor with Special Reference to the Cure Rate by Multimodality Treatment.
Kwan Sub Chung1, Duk Jin Yun1, Byung Soo Kim2, Dong Sik Kim2
1Department of Pediatrics, Yonsei University College of Medicine Seoul, Korea.
2Yonsei Cancer Center, Korea.
병합요법에 의한 Wilms 종양의 완치율에 관한 연구
정관섭1, 윤덕진1, 김병수2, 김동식2
1연세대학교 의과대학 소아과학교실
2연세 암센터
Abstract
Wilms' tumor is the most common intra-abdominal malignant tumor of childhood. There has been a progressive improvement in the over all survival rate of children with Wilms' tumor since the introduction of radiotherapy and nephrectomy. Survival has continued to improve with the addition of chemotherapy, initially actinomycin D, and later vincristine. This paper reviewed 34 patients with Wilms' tumor seen between 1965 and 1979 with special references to the significant factors in diagnosis as well as the influence of age, stage of disease and treatment on the prognosis. The usefulness of three modalities of treatment was discussed. A cure rate of 64.9% in the intensive multimodaliy treatment group was calculated by the Life Table Method.


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