| A case of benign recurrent intrahepatic cholestasis. |
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Jae Hong Park, Sung Sub Sim, Soo Young Kim, Hee Joo Jeon, Chan Yung Kim |
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Department of Pediatrics, School of Medicine, Pusan National University, Pusan, Korea |
| 양성 재발성 간내 담즙울체증 1례 |
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박재홍, 심성섭, 김수영, 전희주, 김찬영 |
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부산대학교 의과대학 소아과학교실 |
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Received: 3 June 1991 • Accepted: 19 July 1991 |
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| Abstract |
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The clinical picture of beingn recurrent intrahepatic cholestasis (BRIC) consists of multiple epi-
sodes of cholestatic jaundice without extrahepatic bile duct obstruction. Since first description by
Summerskill and Walshe in 1959, almost 100 patients with BRIC have been described. The mechanism
involved in the initiation and perpetution of an episode of cholestasis are unknown. Altered bile acid
metabolism has been proposed to play a role in pathophysiology of the diseases.
The authors recently experienced a case of BRIC in a 15-year-old boy, who had four episodes of
recurrent attack of cholestatic jaundice during 38 months.
The case is reported with the brief review of the literatures.
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| Key Words:
Benign recurrent intrahepatic cholestasis |
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