Disseminated Aspergillosis(An Autopsy Case of a Child with Liver Cirrhosis)

Lee, S.K.; Chi, J.G.; Park, H.S.; Kwon, Y. J.; Hong, Y.W.; Rie, B.H.

Original Article

Journal of the Korean Pediatric Society 1967;10(12):647-652.
Published online December 31, 1967.

Disseminated Aspergillosis(An Autopsy Case of a Child with Liver Cirrhosis)

S.K. Lee¹, J.G. Chi¹, H.S. Park¹, Y. J. Kwon², Y.W. Hong², B.H. Rie²

¹Dept, of Pathology, College of Medicine, Seoul National University
²Dept, of Pediatrics, College of Medicine Seoul National University

全身性Aspergillosis 一肝硬變症을 隨伴한 小兒의 1 部檢例-

李尙園^¹^, 池提根^¹^, 朴孝淑^¹^, 樓奉助^²^, 洪鎔宇^²^, 李炳勳^²

^¹서울大學校醫科大學病理學敎室
^²서울大學校醫科大學小兒科學敎室

Abstract

An autopsy case of disseminated aspergillosis in a 11 years and 9 months old Korean male has been reported. The patient was managed with broad spectrum antibiotics through the hospital stays of two times for liver cirrhosis. At autopsy non-specific granulomatous or suppurative lesions were found in the lungs, endocardium, kidney, thyroid and brain. Microscopically, areas of necrosis with numerous branching mycelia were present in all the lesions of the viscera. These were widespread infarcts of the brain, with invasion of thrombi and blood vessels by the fungi. Morphologically the fungi were composed of inumerable hyphae having true septation and branching of acute angle. Chlamydospores and conidiospores were also frequently observed in the lesions.