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Clinical Reactions and Effect on the Platelet Count in the Peripheral Blood After Live Attenuated Measles Virus (Lirugen) Vaccination

Journal of the Korean Pediatric Society 1969;12(4):175-180.
Published online April 30, 1969.
Clinical Reactions and Effect on the Platelet Count in the Peripheral Blood After Live Attenuated Measles Virus (Lirugen) Vaccination
Jae Choon Lee, Byung II Kim, Doo Hong Ahn, Dong Sup Han
Derartment of Pediatrics, College of Medicine, Kyungpook National University, Taegu, Korea
紅疫生 Vaccine (Lirugen) 接種 後의 臨床反應및 末稍血液 中의 血小板數의 變動에 對하여
李在春, 金炳鎰, 安斗洪, 韓東燮
慶北大學校 醫科大學 小兒科學敎室
Abstract
Live attenuated measles virus (Lirugen) was vaccinated in 14 susceptible children. The mean maximum rectal temperature was 100.2 °F, and anorexia, cough, ri nor rhea were observed in some vaccinated children, but the rashes were not developed in all cases. Total WBC count was mildly decreased 1 week after vaccination which were within normal limits. Differential count showed that lymphocytes were increased 9 days after vaccination, segments were conversely decreased. All vaccinated children showed a fall in platelet counts with a mean maximum fall of 69,000 and it was noted 12 days after vaccination. Warthin-Finkeldey giant cell on the nasal or buccal mucous membrane was not present in all vaccinated children.


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