Clinical Reactions and Effect on the Platelet Count in the Peripheral Blood After Live Attenuated Measles Virus (Lirugen) Vaccination
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Jae Choon Lee, Byung II Kim, Doo Hong Ahn, Dong Sup Han |
Derartment of Pediatrics, College of Medicine, Kyungpook National University, Taegu, Korea |
紅疫生 Vaccine (Lirugen) 接種 後의 臨床反應및 末稍血液 中의 血小板數의 變動에 對하여
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李在春, 金炳鎰, 安斗洪, 韓東燮 |
慶北大學校 醫科大學 小兒科學敎室 |
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Abstract |
Live attenuated measles virus (Lirugen) was vaccinated in 14 susceptible children. The mean maximum rectal temperature was 100.2 °F, and anorexia, cough, ri nor rhea were observed in some vaccinated children, but the rashes were not developed in all cases. Total WBC count was mildly decreased 1 week after vaccination which were within normal limits. Differential count showed that lymphocytes were increased 9 days after vaccination, segments were conversely decreased. All vaccinated children showed a fall in platelet counts with a mean maximum fall of 69,000 and it was noted 12 days after vaccination. Warthin-Finkeldey giant cell on the nasal or buccal mucous membrane was not present in all vaccinated children.
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