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Experimental Study on Insulin acting Areas of the Central Nervous System in BSP Excretion

Journal of the Korean Pediatric Society 1972;15(6):477-492.
Published online June 30, 1972.
Experimental Study on Insulin acting Areas of the Central Nervous System in BSP Excretion
Yung Kil Chang
Department of Pediatrics, College of Medicine, Seoul National University Seoul, Korea
中福神經에 있어 Insidin 이 BSP排泄에 影響을 미치는 部位에 關한 實驗的 硏究
張永吉
Abstract
The object of this study is to investigate the effects of various areas of the central nervous system on BSP excretion of the liver. The Korean male rabbits weighing 1. 8 kg were subjected for study, and 0. 5u of insulin was injected into both regions of the central nervous system symmetrically. The following are observed; 1. There was neither increased in bile nor BSP excretion when such areas as putamen, globus pallidus, anterior hypothalamus, posterior hypothalamis, midmedial hypothalamus, hippocampus, preoptic area, midbrain and nucleus salivarius were injected with insulin respectively. 2. There were markedly increased in both bile and BSP excretion when the three areas; caudate nucleus, midlateral hypothalamus, and mammillahy body were injected with insulin respectively. The above mentioned experimental findings lead this author to conclude the regulating centers which cause to increase in BSP excretion exist in caudate nucleus, midlateral hypothalamus and mammillary bony.


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