| Cushing’s Syndrome in Infancy |
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Pyung Kil Kim1, Ki Sub Chung1, Duk Jin Yun1, Sang Hyon Suh2, Sang Ho Cho3 |
1Department of Pediatrics Yonsei University College of Medicine Seoul, Korea
2Department of Surgery Yonsei University College of Medicine Seoul, Korea
3Department of Pathology Yonsei University College of Medicine Seoul, Korea |
| 嬰兒期에 發病한 Cushing s Syndrome 의 1 例 |
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金炳吉1, 鄭顧燮1, 尹德鎭1, 徐相賢2, 曺湘昊3 |
1延世大學校 醫科大學 小兒科學敎室
2延世大學校 醫科大學 外科學敎室
3延世大學校 醫科大學 病理學敎室 |
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| Abstract |
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There are little reports on the Cushing’s syndrome in children, especially in infancy in Korea. We have found recently a case of Cushing’s syndrome in infancy arising from a female infant. She has been complained from eleven month of age with general obesity including buffalo hump, excessive weight: gain, hirsutism and polyphgagia. Laboratory tests revealed that no thymic shadow in her chest X-ray, retarded bone age, hypertension,increased urinary excretion of 17-OHCS and 17-KS and eosinopsnia but no evidence of osteoporosis iir her long bone series. Two-days dexamethasone test were done and it was found that there were no response to administration of dexamethasone in her urinary excretion of 17-OHCS. IVP study showed that left kidney was displaced to downward than right side and an hen-egg size-radio-opaque shadow on the top of the left kidney. The tumor was removed successfully by anterior transabdominal approach and that was found as a benign adenoma by microscopic study.
Hypertension, eosinopenia and hypokalemia were returned to normal level from 3 days after surgery but
urinary 17-OHCS and 17-KS were returned to normal from two week after surgery. The literature about Cushing’s syndrome in infancy were reviewed and compaired with our case. |
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