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Three Cases of Congenital Syphilitic Nephrotic Syndrome

Journal of the Korean Pediatric Society 1970;13(6):359-364.
Published online June 30, 1970.
Three Cases of Congenital Syphilitic Nephrotic Syndrome
Kwang Jun Kim, Myung Jin Koo, Kyung Shuk Yang
Department of pediatrics, Seoul Red Cross Hospital Seoul, Korea.
Congenital Syphilitic Nephrotic Syndrome 3 例
金光典, 具明珍, 梁康錫
서울赤十字病院 小兒科
Three eases of congenital syphilitic nephrotic syndrome are presented. This is the first report, to our knowledge, in Korea. It is our opinion that the diagnosis of congenital syphilitic nephrotic syndrome is highly probable in case I and HI. Although there were no edema and hypopreteinemia in case I, we believe that the congenital syphilis involved the kindey according to other laboratory findings. Pretreatment level of serum cholesterol was in normal ranges in case M, however, it increased above normal ranges in spite of clinical remission and reduction in qualitative urinary protein with increased serum protein level after treatment for about one month, and it is the problem of further study for us to detect the causes of hypercholesterolemia in this case. In All of our cases presented here were relatively good clinical courses observed after penicillin therapy.

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