| Studies on the Blood Sugar Levels with Time in Neonates |
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Dong Gwan Han |
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Department of Pediatrics, Yonsei University College of Medicine |
| 新生兒 血糖値 變動에 對한 觀察 |
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韓東觀 |
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延世大學校 醫科大學 小兒科學敎室 |
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| Abstract |
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Although there is still disagreement for levels of blood sugar in the neonates of Caucasian race, they have measured true sugar or glucose in blood of newborm infants since 1911." Most authors agree that the blood sugar levels in full-term infants tend to decrease during the first few hours of life and only reach levek that would be in the range of normal adult by one or two weeks of age. Much of this confusion results from differences in technics in collecting, precipitating and analyzing the sugar, as well as the duration of fast before sampling.
Author studies the determinations of blood sugar levels from each of 70 full-term normal newborn infants born in Severance Hospital for 3 months from October to December, 1968. Blood for the sugar determinations by a Somogyi-Nelson micromethod is obtained from a skin punture in the heel of the infants. The 5 times of serial blood sugar determinations from each of 70 newborn infants are made for the first 48 hours. The first sample of blood is : taken with the first 2 hours after birth, and subsequent samples are made at 8 to 10 hours fasting, 12 hours and 48 hours at least 3 hours after lest feeding. The following results are obtained: 1)The average level of blood sugar in 34 cases of male is 46. 5+9. 6 mg/dl. and in 36 cases of female 47. 8±11. 7mg/dl. but their difference is not statistically sinificant. The levels of serial blood sugar determinations were similer in male and female. 2)The average levels of blood sugar in relation to birth weight show 47. 7士9. 5 mg/dl. below
3.20 kg. and 46. 11. 9 mg/dl over 3.21 kg., but their difference is not statistically significant. The value after 8 to 10 hours fasting in former group decreases markedly 3)The serial obs ervations of blood sugar in normal neonates represent a fluctuations for 48 hours. The values at birth decrease markedly from 8 to 10 hours-fasting and begin to rise gradually after milk;= feedings and the blood sugar levels reach a peak about 48 hours later. The blood sugar levels seem to be relateid to fasting period and other factors. 4) The range of blood sugars for the first 48 hours from 350 determinations in 70 neonates is 23 to 98 mg/dl. average value is 47. 2 ±10. 8 mg/dl. and mean ±2 S.D. is 25. 6 to 68. 8 mg/dl. 5)Low values are obtained in 16 determinations, but no signs of symptomatic hypoglycemia are observed. |
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